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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
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2002 2
2003 3
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2019 1
2024 0

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19 results

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Page 1
Keratin 5/14-mediated cell differentiation and transformation are regulated by TAp63 and Notch-1 in oral squamous cell carcinoma-derived cells.
Srivastava SS, Alam H, Patil SJ, Shrinivasan R, Raikundalia S, Chaudhari PR, Vaidya MM. Srivastava SS, et al. Oncol Rep. 2018 May;39(5):2393-2401. doi: 10.3892/or.2018.6298. Epub 2018 Mar 6. Oncol Rep. 2018. PMID: 29512781
Previous research in our laboratory showed that upon K5/14 downregulation in oral squamous cell carcinoma (OSCC)-derived cells, there was an increase in intracellular Notch-1 levels and differentiation markers such as involucrin, keratin 1 and a decrease in tumorigenic pot …
Previous research in our laboratory showed that upon K5/14 downregulation in oral squamous cell carcinoma (OSCC)-derived cells, there …
The urothelial cell line UROtsa transformed by arsenite and cadmium display basal characteristics associated with muscle invasive urothelial cancers.
Hoggarth ZE, Osowski DB, Freeberg BA, Garrett SH, Sens DA, Sens MA, Zhou XD, Zhang KK, Somji S. Hoggarth ZE, et al. PLoS One. 2018 Dec 14;13(12):e0207877. doi: 10.1371/journal.pone.0207877. eCollection 2018. PLoS One. 2018. PMID: 30550540 Free PMC article.
Our laboratory has developed an in-vitro model of urothelial cancer by transforming the immortalized cell line UROtsa with arsenite (As3+) and cadmium (Cd2+). In this study, we characterized the tumors formed by these transformed cell lines as more basal-like based …
Our laboratory has developed an in-vitro model of urothelial cancer by transforming the immortalized cell line UROtsa with arsenite ( …
KRT14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis.
Papafotiou G, Paraskevopoulou V, Vasilaki E, Kanaki Z, Paschalidis N, Klinakis A. Papafotiou G, et al. Nat Commun. 2016 Jun 20;7:11914. doi: 10.1038/ncomms11914. Nat Commun. 2016. PMID: 27320313 Free PMC article.
The urothelium is a specialized epithelium that lines the urinary tract. It consists of three different cell types, namely, basal, intermediate and superficial cells arranged in relatively distinct cell layers. ...Here we show that a minor subpopulation of basal cel …
The urothelium is a specialized epithelium that lines the urinary tract. It consists of three different cell types, namely, basal, in …
Expression of the p53 homologue p63 in early cervical neoplasia.
Quade BJ, Yang A, Wang Y, Sun D, Park J, Sheets EE, Cviko A, Federschneider JM, Peters R, McKeon FD, Crum CP. Quade BJ, et al. Gynecol Oncol. 2001 Jan;80(1):24-9. doi: 10.1006/gyno.2000.5953. Gynecol Oncol. 2001. PMID: 11136565
A correlation was also made between p63 expression and squamous basal cell (keratin 14), endocervical columnar cell (mucicarmine), and cell-cycle specific (Ki-67) markers. ...CONCLUSIONS: In the lower female genital tract, p63 is preferentially expressed in i …
A correlation was also made between p63 expression and squamous basal cell (keratin 14), endocervical columnar cell (mucicarmi …
Regulation of DCIS to invasive breast cancer progression by Singleminded-2s (SIM2s).
Scribner KC, Behbod F, Porter WW. Scribner KC, et al. Oncogene. 2013 May 23;32(21):2631-9. doi: 10.1038/onc.2012.286. Epub 2012 Jul 9. Oncogene. 2013. PMID: 22777354 Free PMC article.
Singleminded-2s (SIM2s) is a member of the bHLH/PAS family of transcription factors and a key regulator of mammary epithelial cell differentiation. SIM2s is highly expressed in mammary epithelial cells and downregulated in human breast cancer. ...To test the hypothesis tha …
Singleminded-2s (SIM2s) is a member of the bHLH/PAS family of transcription factors and a key regulator of mammary epithelial cell di …
Enrichment of genes associated with squamous differentiation in cancer initiating cells isolated from urothelial cells transformed by the environmental toxicant arsenite.
Hoggarth ZE, Osowski DB, Slusser-Nore A, Shrestha S, Pathak P, Solseng T, Garrett SH, Patel DH, Savage E, Sens DA, Somji S. Hoggarth ZE, et al. Toxicol Appl Pharmacol. 2019 Jul 1;374:41-52. doi: 10.1016/j.taap.2019.04.021. Epub 2019 Apr 29. Toxicol Appl Pharmacol. 2019. PMID: 31047981 Free PMC article.
Our lab has developed an in-vitro model of urothelial carcinoma by exposing the immortal, but non-tumorigenic bladder cell line, the UROtsa, to arsenite (As(3+)). These transformed cells form tumors in immune-compromised mice, which resemble urothelial carcinomas with comp …
Our lab has developed an in-vitro model of urothelial carcinoma by exposing the immortal, but non-tumorigenic bladder cell line, the …
MicroRNA-21 is an important downstream component of BMP signalling in epidermal keratinocytes.
Ahmed MI, Mardaryev AN, Lewis CJ, Sharov AA, Botchkareva NV. Ahmed MI, et al. J Cell Sci. 2011 Oct 15;124(Pt 20):3399-404. doi: 10.1242/jcs.086710. Epub 2011 Oct 7. J Cell Sci. 2011. PMID: 21984808 Free PMC article.
These included selected BMP-dependent tumour-suppressor genes (Pten, Pdcd4, Timp3 and Tpm1) negatively regulated by miR-21, as well as miR-21-independent Id1, Id2, Id3 and Msx2 that predominantly mediate the effects of BMPs on cell differentiation. In primary keratinocytes …
These included selected BMP-dependent tumour-suppressor genes (Pten, Pdcd4, Timp3 and Tpm1) negatively regulated by miR-21, as well as miR-2 …
Different proliferative activity of the glandular and myoepithelial lineages in benign proliferative and early malignant breast diseases.
Bánkfalvi A, Ludwig A, De-Hesselle B, Buerger H, Buchwalow IB, Boecker W. Bánkfalvi A, et al. Mod Pathol. 2004 Sep;17(9):1051-61. doi: 10.1038/modpathol.3800082. Mod Pathol. 2004. PMID: 15254552 Free article.
In contrast, noninvasive breast malignancies were composed of a monotonous proliferation of CK 8/18/19(+) neoplastic glandular cells. These findings indicate a significant role of progenitor cells in the development of benign proliferative breast diseases and lend support …
In contrast, noninvasive breast malignancies were composed of a monotonous proliferation of CK 8/18/19(+) neoplastic glandular cells. …
Expression of dominant negative Jun inhibits elevated AP-1 and NF-kappaB transactivation and suppresses anchorage independent growth of HPV immortalized human keratinocytes.
Li JJ, Rhim JS, Schlegel R, Vousden KH, Colburn NH. Li JJ, et al. Oncogene. 1998 May 28;16(21):2711-21. doi: 10.1038/sj.onc.1201798. Oncogene. 1998. PMID: 9652737
AP-1 transactivation appears to be required for mouse JB6 cell neoplastic transformation induced by the tumor promoter TPA or epidermal growth factor (EGF). Exposure to AP-1 transrepressing retinoids and glucocorticoids and expression of a dominant negative c …
AP-1 transactivation appears to be required for mouse JB6 cell neoplastic transformation induced by the tumor promoter …
Ultraviolet B irradiation increases keratin 5 and keratin 14 expression through epidermal growth factor receptor of SV40-transformed human keratinocytes.
Kinouchi M, Takahashi H, Itoh Y, Ishida-Yamamoto A, Iizuka H. Kinouchi M, et al. Arch Dermatol Res. 2002 Feb;293(12):634-41. doi: 10.1007/s00403-001-0284-9. Epub 2002 Jan 23. Arch Dermatol Res. 2002. PMID: 11875647
UVB irradiation (10 mJ/cm(2)) increased keratin 5 and keratin 14 mRNAs and proteins without affecting cell viability. Upregulation of keratin 5 and keratin 14 was dependent on the dose of radiation: the effect was observed at 5 mJ/cm(2) and the maximal effect was observed …
UVB irradiation (10 mJ/cm(2)) increased keratin 5 and keratin 14 mRNAs and proteins without affecting cell viability. Upregulation of …
19 results